Receiving and preparing genetic samples
is the first step in the process of studying genetic
material at GSK.
The Samples Management Lab:
receives
blood and other body fluid
from partners in the Disease Networks and from
pharmacogenetic studies, including all phases
of clinical trials. This lab then logs information
about those samples into the computer database;
Each
sample is labelled with a unique bar code,
which is scanned into a database. The
database stores information about that
sample, including which study the patient
is enrolled in, which clinical site collected
the sample, the volume and concentration
of the sample and the sample location
in the laboratory.
coordinates
the extraction of DNA from blood samples and performs
quality control checks on the DNA samples;
DNA
is extracted from the samples, which are
tested to ensure that there is adequate
DNA for analysis.
stores
the samples for future reference;
DNA
samples from participants in clinical studies
are stored in freezers at -80° C.
and
prepares the samples for use by GSK's Discovery
Genetics Divisions and collaborators at clinical
sites.
DNA
samples are transferred to plates and then
dehydrated before being sent to the genotyping
or DNA sequencing laboratories.
Virtual Tour of Sample
Management
Take a virtual tour
of the genetics research labs at GlaxoSmithKline.
You will need the QuickTime plug-in to
view the tour. Click
here to download the appropriate plug-in.
Position your cursor over the picture
above and hold down the mouse button. Drag the cursor
around to where you want to look while continuing to
hold the button down.
Move your cursor over the picture without
holding the mouse button down. Your cursor will change
to a pointing finger when you encounter a "hot
spot." Clicking the mouse will open a window that
displays video clips or photographs with more detail.
Your pointer will change to an arrow when you encounter
a jump point. Clicking the mouse on a jump point will
move you to another place in the virtual tour of the
lab.
Click the button with the "?"
to reveal all the "hot spots."
