1.	The human genome is
	a. Made of RNA
	b. 3 billion base pairs in length
	c. Over one million genes
	d. The same in every person
2.	Which of these statements about DNA is not true?
	a. DNA contains the instructions needed to make proteins.
	b. The amount of DNA that differs from one person to another is less than 1%.
	c. DNA controls how much of a protein will be made and when it will be made.
	d. DNA is made up of many chromosomes.
3.	Choose the definition that is NOT correct:
	a. Genetics is the study of traits that are passed from parent to offspring and the variation of those traits in individuals.
	b. Genomics is the analysis of DNA and its products (RNAs and proteins).
	c. Pharmacogenetics is the study of variation in response to medicine due to hereditary traits in populations.
	d. Bioinformatics is the study of how information is conveyed in biological systems.
4.	Autosomal recessive conditions:
	a. Are often associated with deficient enzyme activity.
	b. Always contain the same mutation in both genes.
	c. Are more variable than autosomal dominant conditions.
	d. Are likely to affect the children of affected individuals.
5.	A target ________________.
	a. is a component in a biochemical pathway
	b. may influence a disease state
	c. is often a protein
	d. all of the above
6.	Differing responses among individuals to the same type or dose of medicine may have a genetic basis.
	a. True
	b. False
7.	Pharmacogenetics focuses on the ______________.
	a. genetic basis of disease
	b. genetic basis of inheritance
	c. genetic basis of a patient's response to a medicine
8.	Succinylcholine is a muscle relaxant widely used during anesthesia. About 1/3000 Caucasians are unable to break down succinylcholine, resulting in prolonged apnea (no spontaneous breathing) after an operation. This effect is due to impaired activity of the enzyme cholinesterase, which inactivates succinylcholine. Mr. K, aged 40, has had difficulty breathing after anesthesia in the past. All of the following statements about his case are correct EXCEPT:
	a. A biochemical test could be performed to assess his ability to break down succinylcholine.
	b. The absence of a family history of this problem means it probably is not a genetic condition.
	c. Family members should be made aware of Mr. K's history.
	d. Knowledge of this history might alter the drugs used for Mr. K's anesthesia.
9.	Medicine Response Tests are being used to predict how a person will react to a drug.
	a. True
	b. False
10.	Select the correct answers for the two blanks in the following sentence: Correlation of a patient's _________ with a patient's _________ may lead to "personalized" medicines.
	a. genotype, family history
	b. response to a medicine, genotype
	c. symptoms, genotype
	d. family history, response to a medicine
11.	DNA consists of
	a. nucleotides
	b. chromosomes
	c. two twisting sugar-phosphate backbones
	d. chromatids
	e. a and d
12.	Most genetic differences among humans are accounted for by
	a. different genomes
	b. different sugar-phosphate backbones in the DNA
	c. different base pair sequences
	d. different genetic materials
13.	Most genetic mutations are
	a. harmful
	b. neutral
	c. wide-spread
	d. beneficial
14.	An egg cell contains
	a. Half the normal number of chromosomes (23)
	b. All of the mother's alleles
	c. No sex chromosomes
	d. A and B
15.	If brown eye color (B) is dominant over blue eye color (b), then we know
	a. The phenotype and genotype of a brown-eyed person
	b. The phenotype and genotype of a blue-eyed person
	c. The genotype of a brown-eyed person
	d. ONLY the phenotype of a blue-eyed person
16.	Pick the false statement about SNPs.
	a. They are one type of genetic marker.
	b. They are used to confirm who is a child's father.
	c. They occur frequently throughout the human genome.
	d. They can be used to predict a person's risk of some diseases or a person's response to a medicine.
17.	All Medicine Response Tests involve examining an individual's DNA.
	a. True
	b. False
18.	Genomics is the study of the _________, _________ and __________ of genes. I. DNA, RNA and protein products II. evolution, bioinformatics and chemistry III. sequence, function and interactions IV. heredity, similarity and implications
	a. II and III
	b. IV only
	c. I and III
	d. I and IV
19.	On average, about 1 in every 5,000 possible new medicines eventually is approved and marketed.
	a. True
	b. False
20.	Many important ethical, legal and social issues related to genetic research still need to be addressed by all those affected - individuals, health care providers, regulatory and government agencies, insurance companies, employers, and the pharmaceutical industry.
	a. True
	b. False